The ketogenic (keto) diet has been studied for its potential to reduce inflammation through several mechanisms, as supported by scientific research:

1. Reduction in Pro-Inflammatory Cytokines: The keto diet has been shown to lower levels of pro-inflammatory cytokines, such as TNF-α, IL-1β, and IL-6. These cytokines are proteins that play a key role in promoting inflammation¹.
2. Improvement in Insulin Sensitivity: By reducing carbohydrate intake, the keto diet helps improve insulin sensitivity. Better insulin sensitivity is associated with lower levels of inflammation, as insulin resistance is linked to increased production of inflammatory markers¹.
3. Alteration of Gut Microbiome: The keto diet can alter the gut microbiome in a way that reduces intestinal inflammation. A study conducted by scientists at the University of California, San Francisco, found that a keto diet specifically changes the gut microbiome, leading to reduced intestinal inflammation².
4. Reduction in Blood Sugar and Insulin Levels: Lower blood sugar and insulin levels, resulting from the keto diet, can decrease inflammation. High blood sugar and insulin levels are known to contribute to inflammatory processes in the body³.
5. Weight Loss and Reduced Adipose Tissue: The keto diet promotes weight loss, which can reduce inflammation. Excess adipose (fat) tissue is associated with increased inflammation, so reducing body fat can help lower inflammatory markers¹.

If you’re considering the keto diet for its anti-inflammatory benefits, it’s best to consult with a healthcare provider to ensure it’s appropriate for your individual health needs.

⁴: BMC Medicine ¹: Frontiers in Medicine ³: Texas Real Food ²: Harvard SITN